Intracranial aneurysms are the leading cause of hemorrhagic stroke. One of the established treatment approaches is the embolization induced by coil insertion. However, the prediction of treatment and subsequent changed flow characteristics in the aneurysm is still an open problem. In this work, we present an approach based on a patient-specific geometry and parameters including a coil representation as inhomogeneous porous medium. The model consists of the volume-averaged Navier-Stokes equations for a non-Newtonian blood rheology. We solve these equations using a problem-adapted lattice Boltzmann method and present a comparison between fully-resolved and volume-averaged simulations. The results indicate the validity of the model. Overall, this workflow allows for patient specific assessment of the flow due to potential treatment.

翻译：颅内动脉瘤是出血性中风的主要原因。已确立的治疗方法之一是通过弹簧圈植入诱发栓塞。然而，对动脉瘤内治疗效果的预测以及随之改变的血流特性仍是一个未解决的问题。本研究提出了一种基于患者特异性几何结构与参数的方法，其中将弹簧圈表示为非均匀多孔介质。该模型包含适用于非牛顿血液流变学的体积平均Navier-Stokes方程组。我们采用针对问题定制的格子玻尔兹曼方法求解这些方程，并对全解析模拟与体积平均模拟进行了对比分析。结果表明该模型具有有效性。总体而言，该工作流程能够针对潜在治疗方案进行患者特异性的血流评估。