Cerebral blood flow and perfusion can be estimated using tracer dilution experiments. Accurate estimation of blood flow parameters is a crucial part of medical imaging for effective diagnosis and treatment. This study explores two themes: (i) the derivation of the gamma variate function as a response tracer infusion and (ii) the estimation of impulse and residue functions from tracer dilution curves parameters via the least squares method.
翻译:脑血流量及灌注可通过示踪剂稀释实验进行估算。血流参数的精确估计是医学影像实现有效诊断与治疗的关键环节。本研究探讨两个主题:(i)作为示踪剂注入响应的伽玛变异函数推导;(ii)通过最小二乘法从示踪剂稀释曲线参数中估计脉冲响应函数及残余函数。