Diffusion models achieve high-quality image generation but remain computationally expensive due to iterative denoising across many timesteps. Existing acceleration methods mainly reduce per-sample latency, but gains along this axis are becoming saturated. We instead explore an orthogonal throughput-oriented direction by processing multiple samples within a single denoising evaluation. To this end, we propose ManiFusion, a backbone-agnostic framework for multi-sample generation through fused-space computation. ManiFusion jointly processes multiple samples by fusing them before the denoising backbone and separating them afterward through unfusion. We provide a geometric perspective on how multiple samples can share a fused representation while retaining the information needed to guide their individual generation trajectories. To better align fusion allocation with denoising stages, ManiFusion uses Trajectory-Fusion Scheduling (TFS), which dynamically adjusts fusion factors throughout sampling. ManiFusion generalizes across diffusion families, including both U-Net and transformer backbones in pixel and latent spaces. We further show that ManiFusion composes with existing acceleration methods and reaches throughput regimes unattainable by prior approaches with minimal quality degradation.

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