The rise of polyglot data management and AI-ready database architectures has created a complex design space across diverse database paradigms. However, architecture selection in modern enterprise environments continues to rely heavily on ad-hoc engineering intuition, with limited systematic frameworks to guide decision-making across heterogeneous database systems. This paper introduces a unified cross-paradigm evaluation and selection framework for database architecture design in AI-ready data platforms. The framework is based on nine architectural dimensions and incorporates a structured multi-stage selection process involving workload characterization, constraint filtering, and compatibility scoring to enable systematic comparison and decision-making. To ground the framework, we conduct a structured comparative analysis across thirteen major database paradigms spanning transactional, analytical, and AI-oriented systems. This analysis reveals three recurring patterns in database evolution: decoupling of storage and compute, workload-driven specialization, and convergence toward integrated AI-ready platforms. The proposed framework is demonstrated through a representative enterprise case study in financial fraud detection, illustrating how hybrid, polyglot architectures emerge as optimal solutions for multidimensional workload requirements. The cross-paradigm analysis culminates in an AI-ready reference architecture that integrates lakehouse storage, feature processing, and semantic retrieval layers as the unified substrate for modern analytics, machine learning, and Retrieval-Augmented Generation applications.

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