Hypertension is a global health concern with an increasing prevalence, underscoring the need for effective monitoring and analysis of blood pressure (BP) dynamics. We analyzed a substantial BP dataset comprising 75,636,128 records from 2,054,462 unique patients collected between 2000 and 2022 at Emory Healthcare in Georgia, USA, representing a demographically diverse population. We examined and compared population-wide statistics of bivariate changes in systolic BP (SBP) and diastolic BP (DBP) across sex, age, and race/ethnicity. The analysis revealed that males have higher BP levels than females and exhibit a distinct BP profile with age. Notably, average SBP consistently rises with age, whereas average DBP peaks in the forties age group. Among the ethnic groups studied, Blacks have marginally higher BPs and a greater standard deviation. We also discovered a significant correlation between SBP and DBP at the population level, a phenomenon not previously researched. These results emphasize the importance of demography-specific BP analysis for clinical diagnosis and provide valuable insights for developing personalized, demography-specific healthcare interventions.

翻译：高血压是全球性健康问题，患病率持续上升，凸显了对血压动态进行有效监测与分析的迫切需求。本研究分析了包含2000年至2022年间美国佐治亚州埃默里医疗系统采集的2,054,462名患者共75,636,128条记录的血压数据集，该数据具有广泛的人口学多样性。我们通过性别、年龄和种族/民族维度，系统研究并比较了收缩压（SBP）与舒张压（DBP）双变量变化的人群统计特征。分析显示：男性血压水平高于女性，并呈现独特的年龄相关血压变化曲线。值得注意的是，平均收缩压随年龄持续升高，而平均舒张压则在40岁年龄组达到峰值。在研究的种族群体中，非裔美国人的血压值略高且标准差更大。我们还发现人群水平上SBP与DBP存在显著相关性——这一现象此前尚未被研究。这些结果强调了在临床诊断中开展人口学特异性血压分析的重要性，并为制定个性化、针对性的人群健康干预措施提供了重要依据。