Inspired by the well-established variance-based methods for global sensitivity analysis, we develop a local total sensitivity index that decomposes the global total sensitivity conditions by independent variables' values. We employ this local sensitivity index in a new method of experimental design that sequentially and adaptively samples the domain of a multivariate function according to local contributions to the global variance. The method is demonstrated on a nonlinear illustrative example that has a three-dimensional domain and a three-dimensional codomain, but also on a complex, high-dimensional simulation for assessing the industrial viability of the production of bioproducts from biomass.

翻译：在全球敏感度分析的既定差异分析方法的启发下,我们开发了一个地方性全面敏感度指数,通过独立变量的值分解全球全面敏感度条件。我们在一种新的实验设计方法中使用了这种地方敏感度指数,根据当地对全球差异的贡献,按顺序和适应性地对多变量函数的范围进行抽样。该方法体现在一个非线性示例中,该示例有一个三维域和一个三维共域,但也有一个复杂的高维模拟,用于评估生物量生物产品生产的工业可行性。