Collecting and labeling diverse test datasets for evaluating Deep Neural Networks (DNNs) is costly and time-consuming. This has motivated coverage-guided fuzzing techniques that generate defect-revealing corner cases from limited test data. However, their effectiveness depends heavily on configuration choices, particularly coverage criteria and seed-selection strategies. We present a configuration-oriented analysis and decision guidelines for scalable DNN fuzzing targeting two bottlenecks: inefficient seed utilization and the cost of coverage guidance. Our analysis shows that existing seed-selection strategies repeatedly prioritize a small subset of inputs, leaving many collected seeds unexplored. To address this issue, we propose Equalized Sampling, a constraint-based strategy that increases mean seed queue utilization to 77%, improving on prior approaches by 13 percentage points. We further evaluate 84 fuzzing configurations on four benchmark datasets: MNIST, SVHN, GTSRB, and CIFAR-100. Results show that the non-structural criteria LSCD, LSC, and MDSC achieve coverage outcomes comparable to structural and alternative non-structural criteria while requiring substantially less computation. These criteria also promote broad behavioral exploration of the DNN under test, reducing the need to monitor multiple coverage metrics. Among them, LSCD provides a modest but consistent runtime advantage. Finally, we show that retraining with generated corner cases improves generalization robustness by up to 77 percentage points on average without degrading performance on the original test distribution. Together, these findings provide a practical blueprint for selecting fuzzing configurations that balance efficiency, behavioral exploration, and model hardening.

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