Cloud-native container orchestration requires resource schedulers capable of balancing infrastructure expenditure, fault resilience, and node utilisation. Conventional reinforcement learning approaches typically rely on monolithic single-agent models that suffer from gradient interference and reward dilution when mapping conflicting operational goals into a single scalar reward. We present Agentic-Kube, a cooperative multi-agent reinforcement learning framework designed for real-time Kubernetes pod placement. The architecture decomposes multi-objective scheduling into a tripartite optimisation space managed by dedicated sub-agents for cost minimisation, anti-affinity fault tolerance, and vector resource balancing. Agentic-Kube integrates a bipartite Graph Convolutional Network to capture dynamic host-pod dependencies, a two-stage monotonic QMIX value factorisation network to maintain joint action value coherence, and a plurality voting consensus mechanism with action feasibility masking against allocatable node predicates. We evaluate the framework across live heterogeneous Google Kubernetes Engine deployments and macro-scale cluster environments spanning 50 to 1,000 nodes under empirical Alibaba trace data, diurnal microservice variations, and flash-crowd bursts. Across physical and simulated evaluations, Agentic-Kube consistently achieves Pareto-efficient placements. In diurnal microservice workloads, it reduces anti-affinity service collisions to 7.11%, representing a 53.0% relative reduction compared to the default Kubernetes scheduler. Under Alibaba traces, the policy achieves a 65.15% spot instance allocation ratio, while macro-scale benchmarks demonstrate scaling up to 1,000 nodes with mean decision latencies under 17ms and 99th-percentile latencies under 31ms, executing without container restart failures and operating well within standard scheduling admission timeouts.
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