This thesis proposes a framework for "responsible intelligence" to address AI's critical challenges in safety, ethics, and cultural sensitivity. It advances three core areas: First, it improves domain adaptation in specialized fields using active learning and graph-based knowledge to reduce hallucinations. Second, it enhances ethical rigor via a novel decoding-time alignment mechanism that proactively blocks harmful text generation in real-time. Finally, it ensures cultural and multilingual safety through language-specific steering that respects diverse linguistic and social norms. Ultimately, this work provides a blueprint for building next-generation AI that is contextually knowledgeable, ethically sound, and culturally adaptable.

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