Nanodevices with Terahertz (THz)-based wireless communication capabilities are providing a primer for flow-guided localization within the human bloodstreams. Such localization is allowing for assigning the locations of sensed events with the events themselves, providing benefits in precision medicine along the lines of early and precise diagnostics, and reduced costs and invasiveness. Flow-guided localization is still in a rudimentary phase, with only a handful of works targeting the problem. Nonetheless, the performance assessments of the proposed solutions are already carried out in a non-standardized way, usually along a single performance metric, and ignoring various aspects that are relevant at such a scale (e.g., nanodevices' limited energy) and for such a challenging environment (e.g., extreme attenuation of in-body THz propagation). As such, these assessments feature low levels of realism and cannot be compared in an objective way. Toward addressing this issue, we account for the environmental and scale-related peculiarities of the scenario and assess the performance of two state-of-the-art flow-guided localization approaches along a set of heterogeneous performance metrics such as the accuracy and reliability of localization.

翻译：具有太赫兹无线通信能力的纳米设备正为人体血流中的流引导定位提供基础。这种定位能够将感知事件的位置与事件本身相关联，从而在精准医疗领域带来早期精确诊断、降低成本和创伤性等益处。流引导定位仍处于初级阶段，仅有少数研究针对该问题。然而，现有解决方案的性能评估已采用非标准化方式进行，通常仅基于单一性能指标，且忽略了在此尺度下（如纳米设备有限能量）和此类挑战性环境（如体内太赫兹传播的极端衰减）相关的重要方面。因此，这些评估的真实性较低，无法进行客观比较。为解决该问题，我们考虑了该场景的环境和尺度相关特殊性，并基于一组异构性能指标（如定位准确性和可靠性），评估了两种最先进的流引导定位方法的性能。