glmnet is a widely adopted R package for lasso estimation due to its computational efficiency. Despite its popularity, glmnet sometimes yields solutions that are substantially different from the true ones because of the inappropriate default configuration of the algorithm. The accuracy of the obtained solutions can be improved by appropriately tuning the configuration. However, improving accuracy typically increases computational time, resulting in a trade-off between accuracy and computational efficiency. Therefore, it is essential to establish a systematic approach to determine appropriate configuration. To address this need, we propose a unified data-driven framework specifically designed to optimize the configuration by balancing the trade-off between accuracy and computational efficiency. We generate large-scale simulated datasets and apply glmnet under various configurations to obtain accuracy and computation time. Based on these results, we construct neural networks that predict accuracy and computation time from data characteristics and configuration. Given a new dataset, our framework uses the neural networks to explore the configuration space and derive a Pareto front that represents the trade-off between accuracy and computational cost. This front allows us to automatically identify the configuration that maximize accuracy under a user-specified time constraint. The proposed method is implemented in the R package 'glmnetconf', available at https://github.com/Shuhei-Muroya/glmnetconf.

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