Many real-world networks are incomplete, making link prediction a fundamental challenge in network science. To train parameters and evaluate algorithms, observed links are usually divided into three subsets, namely training, validation, and probe sets. This division implicitly involves two sampling processes: first-stage sampling yields the probe set and second-stage sampling obtains the variation set. To date, our understanding of how these two sampling processes affect algorithm performance remains quite limited. To address this issue, we propose a sampling scheme called $β$-sampling, where the sampling probability of a link is proportional to the product of the degrees of its two endpoints raised to the power of $β$. Experiments on 45 real-world networks reveal that the structural characteristics of missing links, as simulated via varying probe sets, substantially impact prediction accuracy. When missing links tend to connect high-degree nodes, such links can be predicted accurately with ease. Furthermore, even with a fixed probe set, second-stage sampling still exerts a significant influence on prediction accuracy. Notably, the optimal second-stage sampling strategy differs from \textit{random sampling} (which randomly selects links to form the validation set) and \textit{consistent sampling} (which guarantees that links in the validation and probe sets share identical structural characteristics).

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