We prove a sharp lower bound for growing-degree polynomial estimation in the symmetric rank-one matrix estimation problem. The observation is \[ \boldsymbol{Y}=\frac{1}{\sqrt{n}} \boldsymbolθ \boldsymbolθ^{\top}+\boldsymbol{W}, \] where the coordinates of $\boldsymbolθ$ are independent with a common, fixed sub-Gaussian distribution $π_Θ$ satisfying $\mathbb E[Θ]\neq0$, and $\boldsymbol{W}$ is symmetric with independent standard Gaussian upper-triangular entries. For every such prior, we give an explicit finite-dimensional bound implying that every sequence of polynomial estimators of degree $D(n)=o(n^{1/60})$ has normalized mean-square error with limit inferior at least $\mathbb E[Θ^2]-q_{\mathsf{amp}}$, the limiting error of Bayes approximate message passing (AMP). This extends the constant-degree equivalence of Montanari and Wein~\cite{montanari2025equivalence} to growing degree under the same prior assumptions. Combined with their polynomial approximation of fixed-iteration AMP, the bound identifies the exact limiting low-degree MMSE whenever $D(n)\to\infty$ within this range. It thereby answers the growing-degree AMP-equivalence question discussed in~\cite{wein2025computational, maleki2026high} for nonzero-mean sub-Gaussian priors in the stated degree range. We also obtain a moment-dependent finite-dimensional lower bound for any nonzero-mean prior with all moments finite. The proof bounds low-degree MMSE using \emph{conditional} joint cumulants and a refined application of Jensen's inequality. The conditional cumulants are defined using an auxiliary Gaussian channel $\boldsymbol{R}$ calibrated to the AMP fixed point. This retains signal dependence that is lost in unconditional cumulant bounds and produces the cancellations needed for quantitative control as the degree grows.

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