We introduce Cost-Aware (CA) Sequential Hypothesis Testing (CASHT), in which an active decision-maker selects sensing actions with different, random costs to identify the true hypothesis under an average-error constraint $δ$, while minimizing the expected total cost (rather than the number of samples). For fixed costs, we prove that the optimal expected total cost scales as $Θ(\log(1/δ))$, and is achievable by Multihypothesis Sequential Probability Ratio Test-based procedures. We show that the CA design principle is to maximize the ratio of expected information gain to expected cost under the policy-induced action distribution. Guided by this principle, we adapt two classic policies to the CA setting and establish their asymptotic optimality. We then treat random costs under two revelation models: ex-post, where costs are disclosed only after a sample is obtained, and the cost-error tradeoff coincides with the fixed-cost case, and ex-ante, where costs accrue before acquisition, and the decision maker may cancel an action mid-operation. For the ex-ante model, we characterize when cancellation lowers the total cost and analyze several cost distributions in detail. Simulations confirm our findings that the CA variants consistently reduce total cost relative to their classic counterparts, and when action cancellation helps or hurts.

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