Co-speech gesture video generation aims to synthesize realistic, audio-driven portrait videos from a single reference image and a speech signal. Despite advances in visual quality, diffusion-based approaches still suffer from degraded local details and imperfect audio-visual alignment. We present PAGE (Parts-Aware GuidancE), a general, backbone-agnostic optimization framework for diffusion-based generation that enhances local spatial fidelity and global audio-visual consistency at both the training-objective and denoising-trajectory levels. During training, we propose Parts-Specific Reweighting (PSR), which adaptively increases supervision in semantically important regions such as lips, eyes, and hands, improving visual fidelity in perceptually critical areas. During inference, we introduce Consistency Classifier Guidance (CCG), an audio-conditioned latent classifier that identifies and corrects audio-visual inconsistencies in the generated video. We further design Differential Guidance (DG), an efficient inference strategy that refines facial and body motion separately while avoiding cross-region interference. To enable large-scale evaluation, we construct the Chinese Announcer Speech (CAS) dataset, the first comprehensive Chinese benchmark for co-speech gesture portrait video generation. Compared with the widely used PATS dataset, CAS includes substantially more identities, video clips, and scene diversity. Extensive experiments on both PATS and CAS demonstrate that PAGE achieves state-of-the-art performance in perceptual quality, gesture diversity, and audio-visual alignment. Project page: https://aigc-explorer.github.io/PAGE/.

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