Single image reflection removal (SIRR) is challenging in real scenes, where reflection strength varies spatially and reflection patterns are tightly entangled with transmission structures. This paper presents a diffusion model with prior modulation framework (FUMO) that introduces explicit priors for spatially adaptive conditioning and structurally faithful restoration. Two priors are extracted directly from the mixed image, an intensity prior that estimates spatial reflection severity and a high-frequency prior that captures detail-sensitive responses via multi-scale residual aggregation. We propose a coarse-to-fine training paradigm. In the first stage, these cues are combined to gate the conditional residual injections, focusing the conditioning on regions that are both reflection-dominant and structure-sensitive. In the second stage, a fine-grained refinement network corrects local misalignment and sharpens fine details in the image space. Experiments conducted on both standard benchmarks and challenging images in the wild demonstrate competitive quantitative results and consistently improved perceptual quality. The code is released at https://github.com/Lucious-Desmon/FUMO.

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