Hyperspectral images (HSIs) are often degraded by mixed noise, including band-dependent Gaussian perturbations and structured artifacts such as stripes, dead-lines, and impulse noise. Most deep denoisers regress the clean image directly, entangling signal and structured noise. We instead model HSI denoising as $\Y=\A\X+\Snoise+\Nnoise$, where $\A\X$ is a low-rank spectral-subspace (unmixing) reconstruction, $\Snoise$ is structured sparse noise and $\Nnoise$ is residual Gaussian noise. The resulting regularized optimization problem is unrolled into AXS-Net, a $K$-stage alternating proximal-point framework. Each stage combines an analytic spectral-basis gradient step, an SSX-Block proximal operator for abundance coefficients, and an SBlock proximal operator for the structured residual with column-consistent and sparse priors. This optimization correspondence exposes interpretable endmembers, abundance maps, and structured-noise estimates. Across ICVL, CAVE, and Harvard datasets and five noise configurations, the proposed AXS-Net achieves strong in-domain accuracy and competitive zero-shot transfer, with consistent gains across all five noise regimes on ICVL and Harvard. The recovered structured-noise closely follows the synthetic reference, and the recovered spectral basis is smooth and band-ordered rather than an arbitrary set of latent channels.

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