Spatio-temporal forecasting is a cornerstone of logistics, urban planning, and intelligent transportation systems. However, constrained by deployment costs and maintenance resources, sensor networks often lack comprehensive spatial coverage, rendering Forecast Unobserved Node States (FUNS) a critical yet formidable challenge. Conventional models rely on historical observations and typically falter when encountering nodes without prior records. To address this, we redefine the problem as a conditional generation task on spatio-temporal graphs and propose GenST, a framework that introduces Large Language Models (LLMs) as a semantic bridge, leveraging a pre-trained LLM fine-tuned to extract rich semantic features from node descriptions, such as functional zones and road network structures, to compensate for missing spatio-temporal signals. Specifically, we design a two-stage generative architecture: a Spatio-Temporal VAE first compresses spatio-temporal dynamics into a latent space, followed by a Generative Transformer (GenT) that reconstructs the future states of unobserved nodes from noise, guided by multi-modal conditions including semantics, geographic coordinates, and neighborhood contexts. Experiments on six traffic and two non-traffic datasets show GenST significantly outperforms existing baselines in zero-shot prediction tasks, demonstrating the practical potential of semantic-guided generation for mitigating spatio-temporal data sparsity.

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