Federated learning (FL) addresses data privacy concerns by enabling collaborative training of AI models across distributed data owners. Wide adoption of FL faces the fundamental challenges of data heterogeneity and the large scale of data owners involved. In this paper, we investigate the prospect of Transformer-based FL models for achieving generalization and personalization in this setting. We conduct extensive comparative experiments involving FL with Transformers, ResNet, and personalized ResNet-based FL approaches under various scenarios. These experiments consider varying numbers of data owners to demonstrate Transformers' advantages over deep neural networks in large-scale heterogeneous FL tasks. In addition, we analyze the superior performance of Transformers by comparing the Centered Kernel Alignment (CKA) representation similarity across different layers and FL models to gain insight into the reasons behind their promising capabilities.

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