Human-Object Interaction (HOI) detection is a longstanding computer vision problem concerned with predicting the interaction between humans and objects. Current HOI models rely on a vocabulary of interactions at training and inference time, limiting their applicability to static environments. With the advent of Multimodal Large Language Models (MLLMs), it has become feasible to explore more flexible paradigms for interaction recognition. In this work, we revisit HOI detection through the lens of MLLMs and apply them to in-the-wild HOI detection. We define the Unconstrained HOI (U-HOI) task, a novel HOI domain that removes the requirement for a predefined list of interactions at both training and inference. We evaluate a range of MLLMs on this setting and introduce a pipeline that includes test-time inference and language-to-graph conversion to extract structured interactions from free-form text. Our findings highlight the limitations of current HOI detectors and the value of MLLMs for U-HOI. Code will be available at https://github.com/francescotonini/anyhoi

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