Memes are a dominant medium for online communication and manipulation because meaning emerges from interactions between embedded text, imagery, and cultural context. Existing meme research is distributed across tasks (e.g., \textit{hate, misogyny, propaganda, sentiment, humour}) and languages, which limits cross-domain generalization. To address this gap, we propose \textsc{MemeLens}, a unified multilingual, multitask explanation-enhanced Vision-Language Model (VLM) for meme understanding. We consolidate $38$ public meme datasets, filter and map dataset-specific labels into a shared taxonomy of $20$ tasks spanning harm, targets, figurative/pragmatic intent, and affect. We present a comprehensive empirical analysis across modeling paradigms, task categories, and datasets. Our findings suggest that robust meme understanding requires multimodal training, varies substantially across semantic categories, and remains sensitive to over-specialization when models are fine-tuned on individual datasets rather than trained in a unified setting. We make the experimental resources (https://github.com/MohamedBayan/MemeLens), model (https://huggingface.co/QCRI/MemeLens-VLM) and datasets (https://huggingface.co/datasets/QCRI/MemeLens) publicly available to the community.

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