Wireless agentic systems enable agents to autonomously perceive, reason, and act. However, existing works neglect the tight coupling between sensing and control in closed-loop integrated sensing and communication (ISAC) systems. In this paper, we propose an active inference (AIF)-driven wireless agentic system for closed-loop ISAC, which jointly optimizes control and sensing resource allocation via backward--forward message passing on a factor graph. The AIF agent maintains a generative model as a digital twin by integrating a localization model for uncertainty-aware state inference and a localization channel knowledge map (CKM) for approximating observation quality during planning. Simulation results demonstrate that the AIF-enabled agent adaptively allocates sensing resources based on spatially varying channel conditions, achieving superior balance among tracking accuracy, control effort, and sensing resource consumption over baseline strategies.

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