In this paper, we develop a generalized framework for constructing reversible linear, reversible self dual and reversible DNA codes using a matrix-theoretic approach based on involutory matrices. The proposed concatenation scheme gives a large class of generator matrices and yields codes with good parameters. The construction is carried out at the level of linear codes and then extended to DNA codes. Using a matrix product approach, we provide a unified method for analysis and proof. Further, we resolve an open problem raised by Oztas et.al. and also we correct and improve some results of them.

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