Functional analysis of the left atrium (LA) plays an increasingly important role in the prognosis and diagnosis of cardiovascular diseases. Echocardiography-based measurements of LA dimensions and strains are useful biomarkers, but they provide an incomplete picture of atrial deformations. High-resolution dynamic magnetic resonance images (Cine MRI) offer the opportunity to examine LA motion and deformation in 3D, at higher spatial resolution and with full LA coverage. However, there are no dedicated tools to automatically characterise LA motion in 3D. Thus, we propose a tool that automatically segments the LA and extracts the displacement fields across the cardiac cycle. The pipeline is able to accurately track the LA wall across the cardiac cycle with an average Hausdorff distance of $2.51 \pm 1.3~mm$ and Dice score of $0.96 \pm 0.02$.
翻译:左心房功能分析在心血管疾病的预后和诊断中发挥着日益重要的作用。基于超声心动图测量的左心房尺寸和应变是有效的生物标志物,但无法完整描述心房变形。高分辨率动态磁共振图像(Cine MRI)能够以更高的空间分辨率和完整的左心房覆盖范围,在三维空间中检查左心房运动与变形。然而,目前尚无专用工具可自动表征左心房的三维运动。因此,我们提出一种工具,可自动分割左心房并提取整个心动周期内的位移场。该流程能够准确追踪心动周期中的左心房壁,平均豪斯多夫距离为$2.51 \pm 1.3~mm$,Dice得分为$0.96 \pm 0.02$。