Digital health, an emerging field integrating digital technologies into healthcare, is rapidly evolving and holds the potential to transform medical practices. Blockchain technology has garnered significant attention as a potential solution to various issues within digital health, including data security, automation, interoperability, and patient data ownership. However, despite the numerous advantages, blockchain faces several challenges and unknowns that must be addressed. This systematic literature review aims to explore the challenges of blockchain applications in digital health and provide best practices to overcome current and future roadblocks. Key issues identified include regulatory compliance, energy consumption, network effects, data standards, and the accessibility of the technology to stakeholders. To ensure the successful integration of blockchain within digital health, it is crucial to collaborate with healthcare stakeholders, pursue continued research and innovation, and engage in open discussions about the technology's limitations and potential.

翻译：数字健康作为一个将数字技术整合到医疗保健中的新兴领域，正在迅速发展并具有改变医疗实践的潜力。区块链技术作为数字健康领域中包括数据安全、自动化、互操作性和患者数据所有权在内各种问题的潜在解决方案而备受关注。然而，尽管具有诸多优势，区块链仍面临若干必须解决的挑战和未知因素。本系统性文献综述旨在探讨区块链在数字健康应用中的挑战，并提供最佳实践以克服当前和未来的障碍。已识别的关键问题包括监管合规、能源消耗、网络效应、数据标准以及技术对利益相关者的可及性。为确保区块链在数字健康领域的成功整合，与医疗保健利益相关者合作、持续推进研究与创新，并就该技术的局限性和潜力开展公开讨论至关重要。