LLM-agents are increasingly used to accelerate the progress of scientific research. Yet a persistent bottleneck is data access: agents not only lack readily available tools for retrieval, but also have to work with unstrcutured, human-centric data on the Internet, such as HTML web-pages and PDF files, leading to excessive token consumption, limit working efficiency, and brittle evidence look-up. This gap motivates the development of \textit{an agentic data interface}, which is designed to enable agents to access and utilize scientific literature in a more effective, efficient, and cost-aware manner. In this paper, we introduce DeepXiv-SDK, which offers a three-layer agentic data interface for scientific literature. 1) Data Layer, which transforms unstructured, human-centric data into normalized and structured representations in JSON format, improving data usability and enabling progressive accessibility of the data. 2) Service Layer, which presents readily available tools for data access and ad-hoc retrieval. It also enables a rich form of agent usage, including CLI, MCP, and Python SDK. 3) Application Layer, which creates a built-in agent, packaging basic tools from the service layer to support complex data access demands. DeepXiv-SDK currently supports the complete ArXiv corpus, and is synchronized daily to incorporate new releases. It is designed to extend to all common open-access corpora, such as PubMed Central, bioRxiv, medRxiv, and chemRxiv. We release RESTful APIs, an open-source Python SDK, and a web demo showcasing deep search and deep research workflows. DeepXiv-SDK is free to use with registration.

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