Lately, a New Transmuted Logistic-exponential (NTLE) distribution was introduced and studied as an extension of the Logistic-Exponential Distribution (LED) with wider applicability in lifetime modelling. However, the maximum likelihood estimates (MLE) of NTLE are not in closed form, and the consistency of the estimates was not examined. Furthermore, some other important properties of NTLE, namely the Shannon entropy, Rényi entropy, stochastic ordering, mode, stress-strength reliability measure, residual life functions (mean and reverse), incomplete moments, Bonferroni and Lorenz curves are yet to be derived. Motivated by this, we derived and studied these important properties and evaluated the performance of ten estimation methods (Maximum Likelihood, Moments, Least Squares, Weighted Least Squares, Maximum product of Spacings, Anderson-Darling, Cramer-von Mises, percentile estimation, and Maximum Goodness-of-Fit methods) for NTLE parameters via Monte Carlo simulation using bias, mean square error, and root mean square error as evaluation criteria. Real-life infectious mortality data fitted to the distributions showed that NTLE has a better fit compared to its base distributions (Exponential and Logistic-Exponential). This finding contributes valuable insights for researchers and practitioners when selecting the appropriate estimation methods, especially for NTLE and some similar distributions in non-closed form.

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