Recent diffusion models have advanced image-conditioned video generation, but their accessibility raises risks of unauthorized manipulation. Image immunization has emerged as a promising defense for Image-to-Video (I2V) protection, yet existing methods often rely on degrading visual quality or temporal coherence. In this work, we revisit I2V immunization as reducing source-content preservation, shifting the focus from output degradation to weakening source-conditioned content propagation. To this end, we propose I2V-DETACH, an image immunization method that prevents unauthorized I2V generation through source grounding detachment. I2V models preserve source content by propagating source-image cues into video latents during denoising. Accordingly, I2V-DETACH disrupts this process in two complementary ways: it suppresses source-video grounding to reduce source cue propagation, and strengthens intra-video interactions to shift denoising toward video-side dynamics with reduced reliance on the source image. To obtain informative optimization signals, we initialize auxiliary video latents with source-oriented states that remain within the source-conditioned generation regime while deviating from source-preserving trajectories. Extensive experiments across diverse diffusion architectures show that I2V-DETACH substantially reduces source-content preservation, improves over prior immunization methods, and exhibits strong black-box transferability.

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