Existing navigation systems commonly rely on dedicated depth sensors or explicit depth reconstruction, while learning to generate trajectories directly from RGB images remains challenging due to the sim-to-real domain gap. In this work, we propose Stereo-Planner, an end-to-end vision-to-trajectory framework that enables zero-shot sim-to-real planning from stereo RGB observations. The key idea is to formulate trajectory generation as state- and scale-conditioned querying of latent stereo geometry. A Scene Representor incorporates a pretrained vision grounding foundation model to extract geometric cues shared across simulated and real-world environments, supporting generalization across visual domains. A lightweight Trajectory Decoder then translates these representations into trajectories through interleaved attention, separating trajectory-state interaction from scene-feature retrieval and incorporating the stereo baseline as a metric-scale cue. With these designs, Stereo-Planner is trained entirely on simulated data by minimizing differentiable trajectory costs and deployed directly in real-world environments without fine-tuning. Benchmark results demonstrate strong cross-scene generalization, with a 95% success rate in simulation environments at a commanded speed of 8 m/s, and competitive performance against depth-based planners using only stereo RGB observations for scene perception. Furthermore, deployment on a compact quadrotor equipped with an NVIDIA Orin NX enables autonomous flight at speeds of up to 7 m/s, with a mean onboard vision-to-action inference time of 24.27 ms. The software, simulation environments, and hardware designs will be open-sourced at https://github.com/Stereo-Planner/Stereo-Planner.

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