Platform trials evaluate the efficacy of multiple treatments, allowing for late entry of the experimental arms and enabling efficiency gains by sharing controls. The power of individual treatment-control comparisons in such trials can be improved by utilizing non-concurrent controls in the analysis. We present the R-package NCC for the design and analysis of platform trials using non-concurrent controls. NCC allows for simulating platform trials and evaluating the properties of analysis methods that make use of non-concurrent controls in a variety of settings. We describe the main NCC functions and show how to use the package to simulate and analyse platform trials by means of specific examples.

翻译：平台试验评估多种处理方法的功效,允许试验武器延迟进入,并通过共享控制实现增效。这种试验中个人治疗-控制比较的力量可以通过在分析中使用非动态控制方法得到改进。我们介绍了用于设计和分析使用非动态控制方法进行平台试验的R包式NCC。NCC允许模拟平台试验并评估各种情况下使用非动态控制方法的分析方法的特性。我们描述了非动态控制的主要功能,并展示了如何利用包件以具体实例模拟和分析平台试验。</s>