Wearable devices for continuous electronic health monitoring often capture data at frequent intervals under a dense functional design. The focal point is the analysis of longitudinal functional data, wherein functional trajectories are observed repeatedly over time. This work is motivated by the interest in assessing the efficacy of a noninflammatory medication, meloxicam, on the daily activity levels of household cats with a pre-existing condition of osteoarthritis under a crossover design. An accelerometer records these activity profiles at a minute level over the entire study period. To this aspect, we propose an orthogonal projection-based pseudo-generalized F test to determine the significance of the functional treatment effect under a functional additive crossover model while accounting for carryover effects and baseline covariates. Under mild conditions, we derive the asymptotic null distribution of the test statistic and the theoretical power function when the projection function is estimated from the data. Numerical studies demonstrate that the proposed test maintains size, proves powerful in detecting the smooth effect of meloxicam, and exhibits high efficiency compared to bootstrap-based alternatives. Application of the test on the accelerometric activity profiles reveals a strong positive effect of meloxicam on the joint pain score of the cats after adjusting for other baseline covariates.

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