We characterize structures such as monotonicity, convexity, and modality in smooth regression curves using persistent homology. Persistent homology is a key tool in topological data analysis that detects higher dimensional topological features such as connected components and holes (cycles or loops) in the data. In other words, persistent homology is a multiscale version of homology that characterizes sets based on the connected components and holes. We use super-level sets of functions to extract geometric features via persistent homology. In particular, we explore structures in regression curves via the persistent homology of super-level sets of a function, where the function of interest is - the first derivative of the regression function. In the course of this study, we extend an existing procedure of estimating the persistent homology for the first derivative of a regression function and establish its consistency. Moreover, as an application of the proposed methodology, we demonstrate that the persistent homology of the derivative of a function can reveal hidden structures in the function that are not visible from the persistent homology of the function itself. In addition, we also illustrate that the proposed procedure can be used to compare the shapes of two or more regression curves which is not possible merely from the persistent homology of the function itself.

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