Post-training quantization (PTQ) compresses deep neural networks for deployment under limited memory and computational budgets. However, low-bit (i.e., 2-bit or 4-bit) PTQ often suffers from substantial performance degradation. Most existing PTQ methods operate on an unconstrained full-precision (FP) model and primarily address quantization errors through post-hoc reconstruction. We argue that low-bit PTQ accuracy is limited not only by post-quantization error minimization, but also by the quantization-error tolerance of a FP model itself. In this paper, we propose Efficient Tuning Before Quantization (ETBQ), a pre-conditioning tuning stage for Stochastic Gradient Descent (SGD)-optimized models before PTQ. During tuning, the FP model is optimized under perturbations sampled from the error distributions of weight and activation quantization, guiding the model toward a loss-landscape region that is less sensitive to the subsequent PTQ. Unlike QAT, ETBQ does not train a fake-quantized deployment model, which is computationally and memory intensive. Instead, ETBQ outputs a FP model that can be used by any PTQ backend. Experiments on CIFAR-100, Tiny-ImageNet, ImageNet, and Cityscapes provide consistent evidence that ETBQ improves low-bit PTQ across diverse tasks. Under W2A4 settings, e.g., ETBQ improves over naive PTQ by 2.14\% top-1 accuracy on Tiny-ImageNet and by 5.80\% mIoU on Cityscapes. Code is available at https://github.com/xpxpxp2001xpxpxp/ETBQ.

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