Background Urinary incontinence (UI) is a common health problem that affects the life and health quality of millions of people in the US. We aimed to investigate the association between sitting time and UI. Methods Across-sectional survey of adult participants of National Health and Nutrition Examination Survey 2007-2018 was performed. Weighted multivariable logistic and regression models were conducted to assess the association between sitting time and UI. Results A total of 22916 participants were enrolled. Prolonged sitting time was associated with urgent UI (UUI, Odds ratio [OR] = 1.184, 95% Confidence interval [CI] = 1.076 to 1.302, P = 0.001). Compared with patients with sitting time shorter than 7 hours, moderate activity increased the risk of prolonged sitting time over 7 hours in the fully-adjusted model (OR = 2.537, 95% CI = 1.419 to 4.536, P = 0.002). Sitting time over 7 hours was related to male mixed UI (MUI, OR = 1.581, 95% CI = 1.129 to 2.213, P = 0.010), and female stress UI (SUI, OR = 0.884, 95% CI = 0.795 to 0.983, P = 0.026) in the fully-adjusted model. Conclusions Prolonged sedentary sitting time (> 7 hours) indicated a high risk of UUI in all populations, female SUI and male MUI. Compared with sitting time shorter than 7 hours, the moderate activity could not reverse the risk of prolonged sitting, which warranted further studies for confirmation.

翻译：背景 尿失禁（UI）是影响美国数百万人口生活与健康质量的常见健康问题。本研究旨在探究久坐时间与尿失禁之间的关联。方法 对2007-2018年美国国家健康与营养调查（NHANES）中成年参与者开展横断面研究。采用加权多变量Logistic回归模型评估久坐时间与尿失禁的关联。结果 共纳入22916名参与者。久坐时间延长与急迫性尿失禁（UUI）显著相关（优势比[OR]=1.184，95%置信区间[CI]=1.076~1.302，P=0.001）。在完全调整模型中，与久坐时间不足7小时的患者相比，中等强度活动反而增加久坐时间超过7小时的风险（OR=2.537，95%CI=1.419~4.536，P=0.002）。完全调整模型显示，久坐时间超过7小时与男性混合性尿失禁（MUI）相关（OR=1.581，95%CI=1.129~2.213，P=0.010），亦与女性压力性尿失禁（SUI）相关（OR=0.884，95%CI=0.795~0.983，P=0.026）。结论 久坐时间超过7小时提示全人群急迫性尿失禁、女性压力性尿失禁及男性混合性尿失禁风险升高。与久坐不足7小时相比，中等强度活动无法逆转久坐延长的风险，该结论有待进一步研究验证。