Agentic workflows in materials science relying on hosted commercial models face severe reproducibility, economic, and data-privacy constraints. To explore fully local agentic science, this work evaluates an open-weights Qwen3:4B model executing an autonomous scientific pipeline across varying hardware constraints. Applied to pentagonal two-dimensional materials, the system extracts parameters from unstructured text, translates them into density functional theory (DFT) inputs, and drives simulations to convergence under a strict neurosymbolic architecture where agents propose and deterministic code disposes. The workflow is guarded by verbatim text grounding and multi-pass inference unions to counteract hardware-induced structural collapse. Evaluated against 201 expert judgements, the extractor achieves 95.7% precision (95% CI 90.3-98.1%) and 67.3% recall (59.8-74.0%), ensuring extracted parameters are strictly factual. However, precision identifying absent parameters does not exceed 47.0%, establishing that the measured omission rate constitutes a loose upper bound on true literature incompleteness. Across three hardware configurations, complete GPU residency governs extraction quality more fundamentally than weight or cache precision, raising Matthews correlation from 0.414 to 0.530 at fixed quantisation and to 0.560 with an unquantised cache. A corpus-scale audit indicates only 19 (33.3%) of the 57 studies are reproducible in principle, reporting every method parameter needed to re-initialise the calculation. Driven to convergence, the workflow reproduces published lattice constants with a mean absolute relative error of 2.3% where the relaxed structure retains its prototype, establishing that lightweight open-weights models can reliably drive autonomous agentic workflows when bounded by deterministic code gates.

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