This work presents UGD-FM, a novel unaligned image guided denoising framework based on cross-modal conditional flow matching. Unlike previous approaches that assume spatially aligned inputs or only handle small-baseline rectified pairs, we address a more challenging setting where severe target noise and large-range two-dimensional cross-modal misalignment coexist. Specifically, we formulate guided denoising as a progressive flow matching process, allowing image restoration and aligned guidance aggregation to mutually reinforce each other. To support efficient few-step inference, we introduce a stage-focused and inference-consistent training strategy that focuses on task-critical denoising stages, and mitigates the training-inference mismatch. We further propose adaptive sparse guidance propagation for efficient and reliable large-range matching, regularized by perceptual and geometric auxiliary losses. Experiments demonstrate that UGD-FM achieves state-of-the-art denoising performance with only one or two inference steps, and is compatible with modern single-image restoration backbones.

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