Automated program repair at repository scale requires an agent to locate a fault among thousands of files and synthesize a correct patch. Existing graph-based agents represent how a repository is organized into files, classes, and functions, but they do not model how variable values flow within a procedure, which leaves the agent without the semantic precision that function-level and line-level localization demand. We present ARISE (Agentic Repository-level Issue Solving Engine), a framework-agnostic toolset that builds a multi-granularity program graph, extending structural relationships down to statement-level nodes connected by intra-procedural definition-use edges, and exposes it through a three-tier tool API that mounts on any tool-use agentic framework. The central primitive is data-flow slicing, a queryable agent tool that traces in a single call which statements define or consume a variable of interest. On SWE-bench Lite (300 real GitHub issues across 11 Python repositories) with the open-source Qwen2.5-Coder-32B-Instruct backbone, mounting ARISE on SWE-agent as the host resolves 22.0% of issues (66/300), a 4.7 percentage-point gain over the unmodified SWE-agent baseline under the identical backbone and host. We show this gain is largely attributable to sharper localization, with Function Recall@1 (R@1) rising from 0.43 to 0.60 (a 40% relative gain) and Line R@1 from 0.26 to 0.41 (a 58% relative gain). Controlled ablations attribute the improvement to the data-flow graph rather than the tool schema, and we further mount the same toolset on a second host framework to study its portability. Decoupled from any single scaffold, the graph builder and slicing API form a drop-in toolset for future repair research.

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