Mixed Reality (MR) allows users to interact with digital objects in a physical environment, but several limitations have hampered widespread adoption. Physiologically adaptive systems detecting user's states can drive interaction and address these limitations. Here, we highlight potential usability and interaction limitations in MR and how physiologically adaptive systems can benefit MR experiences and applications. We specifically address potential applications for human factors and operational settings such as healthcare, education, and entertainment. We further discuss benefits and applications in light of ethical and privacy concerns. The use of physiologically adaptive systems in MR has the potential to revolutionize human-computer interactions and provide users with a more personalized and engaging experience.

翻译：混合现实（MR）允许用户在物理环境中与数字对象进行交互，但存在几个限制阻碍了广泛采用。通过检测用户状态的生理自适应系统可以驱动交互并解决这些限制。本文重点介绍了MR中潜在的可用性和交互限制，以及生理自适应系统如何受益于MR体验和应用。我们特别讨论了人因和运行设置（如医疗保健，教育和娱乐）的潜在应用。我们进一步讨论了在伦理和隐私方面的利益和应用。生理自适应系统在MR中的应用有潜力革新人机交互，并为用户提供更个性化和更具吸引力的体验。