Determining the physicochemical properties of a protein can reveal important insights in their structure, biological functions, stability, and interactions with other molecules. Although tools for computing properties of proteins already existed, we could not find a comprehensive tool that enables the calculations of multiple properties for multiple input proteins on the proteome level at once. Facing this limitation, we have developed Multiple Protein Profiler (MPP) 1.0 as an integrated tool that allows the profiling of 12 individual properties of multiple proteins in a significant manner. MPP provides a tabular and graphic visualization of properties of multiple proteins. The tool is freely accessible at https://mproteinprofiler.microbiologyandimmunology.dal.ca/
翻译:确定蛋白质的理化性质可揭示其结构、生物学功能、稳定性及与其他分子相互作用的重要信息。尽管已有计算蛋白质性质的工具,但我们未能找到一种能够同时针对多个输入蛋白质、在蛋白质组水平上批量计算多种性质的综合性工具。针对这一局限性,我们开发了多重蛋白质分析仪1.0(MPP),作为一个集成化工具,能够以显著方式对多种蛋白质的12种个体性质进行分析。MPP提供表格与图形化的方式展示多种蛋白质的性质。该工具可通过https://mproteinprofiler.microbiologyandimmunology.dal.ca/ 免费访问。