Pediatric tumors of the central nervous system are the most common cause of cancer-related death in children. The five-year survival rate for high-grade gliomas in children is less than 20%. Due to their rarity, the diagnosis of these entities is often delayed, their treatment is mainly based on historic treatment concepts, and clinical trials require multi-institutional collaborations. Here we present the CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs challenge, focused on pediatric brain tumors with data acquired across multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. The CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs challenge brings together clinicians and AI/imaging scientists to lead to faster development of automated segmentation techniques that could benefit clinical trials, and ultimately the care of children with brain tumors.

翻译：儿童中枢神经系统肿瘤是导致儿童癌症相关死亡的最常见原因。儿童高级别胶质瘤的五年生存率不足20%。由于此类肿瘤发病率低，其诊断常被延误，治疗主要基于传统治疗理念，且临床试验需要多机构合作。本文介绍了聚焦于儿科脑肿瘤的CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs挑战赛，所使用数据由多个专注于儿科神经肿瘤学及临床试验的国际联盟提供。该挑战赛汇聚了临床医生与人工智能/影像学科学家，旨在加速开发自动化分割技术，从而惠及临床试验并最终改善脑肿瘤患儿的诊疗水平。