In conventional statistical and machine learning methods, it is typically assumed that the test data are identically distributed with the training data. However, this assumption does not always hold, especially in applications where the target population are not well-represented in the training data. This is a notable issue in health-related studies, where specific ethnic populations may be underrepresented, posing a significant challenge for researchers aiming to make statistical inferences about these minority groups. In this work, we present a novel approach to addressing this challenge in linear regression models. We organize the model parameters for all the sub-populations into a tensor. By studying a structured tensor completion problem, we can achieve robust domain generalization, i.e., learning about sub-populations with limited or no available data. Our method novelly leverages the structure of group labels and it can produce more reliable and interpretable generalization results. We establish rigorous theoretical guarantees for the proposed method and demonstrate its minimax optimality. To validate the effectiveness of our approach, we conduct extensive numerical experiments and a real data study focused on education level prediction for multiple ethnic groups, comparing our results with those obtained using other existing methods.

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