Clinical use of finite element analysis requires validation and reproducibility studies. The current study compared two models of vertebral bodies including endplates, on the same experimental dataset and evaluated the influence of the operator on the failure load. Models used were strongly correlated (R2=0.91). The intra-operator reproducibility was 6.4% and 3.5 % for each model. Both simulated results were close to experimental results. The differences in performance could be associated to the differences in segmentation process, mesh (hexahedral vs tetrahedral), material representation and failure criteria. Linear analysis did not decrease model accuracy. Comparison with literature for accuracy and precision shows a wide range of values partly related to the different experimental datasets and the different modelling approaches. Models benchmark using the same experimental dataset are needed to go towards clinical applications.

翻译：有限元分析的临床应用需要验证和可重复性研究。本研究在同一实验数据集上比较了两种包含终板的椎体模型，并评估了操作者对失效载荷的影响。所用模型强相关（R2=0.91）。两种模型的内部操作者可重复性分别为6.4%和3.5%。两种模拟结果均接近实验结果。性能差异可能与分割过程、网格（六面体vs四面体）、材料表征和失效准则的差异有关。线性分析未降低模型精度。与文献中关于精度和准确性的比较显示，存在较大范围的值，部分归因于不同的实验数据集和不同的建模方法。需要基于同一实验数据集进行模型基准测试，以推动临床应用。