Intracranial aneurysms are the leading cause of stroke. One of the established treatment approaches is the embolization induced by coil insertion. However, the prediction of treatment and subsequent changed flow characteristics in the aneurysm, is still an open problem. In this work, we present an approach based on patient specific geometry and parameters including a coil representation as inhomogeneous porous medium. The model consists of the volume-averaged Navier-Stokes equations including the non-Newtonian blood rheology. We solve these equations using a problem-adapted lattice Boltzmann method and present a comparison between fully-resolved and volume-averaged simulations. The results indicate the validity of the model. Overall, this workflow allows for patient specific assessment of the flow due to potential treatment.

翻译：颅内动脉瘤是导致中风的主要原因。经弹簧圈填塞诱导的栓塞是已确立的治疗方法之一，但治疗效果的预测以及动脉瘤内血流特征的变化仍是一个未解难题。本研究提出了一种基于患者特异性几何参数的方法，其中弹簧圈被表示为非均匀多孔介质。模型包含体积平均后的纳维-斯托克斯方程，并考虑了非牛顿血液流变特性。我们采用问题适配的格子玻尔兹曼方法求解这些方程，并将全分辨率模拟与体积平均模拟结果进行了对比。结果表明该模型的有效性。总体而言，该工作流程可针对潜在治疗引起的血流变化进行患者特异性评估。