Regression testing assesses whether software components that have already been developed and tested continue to work correctly after modifications. Ideally, regression testing re-executes the entire test suite after each modification, but this is infeasible in real-world scenarios because of the computational burden; therefore, optimized approaches, such as Test Case Selection, have been developed. The state of the art in regression testing optimization includes both classical approaches, such as Additional Greedy and DIV-GA, and quantum approaches, such as SelectQA, BootQA, and IGDec-QAOA. However, while the former incur high computational costs, the latter are constrained by the physical limitations of currently available quantum machines. This paper extends the evaluation of QAOA-TCS, our quantum approach for the test case selection problem. We thoroughly evaluate its performance, compare it with state-of-the-art classical and quantum approaches, and assess its robustness to quantum noise. The results show that QAOA-TCS outperforms state-of-the-art multi-objective approaches in most cases and maintains stable performance even under high noise levels. In the single-objective formulation, QAOA-based methods perform comparably. In terms of efficiency, our previous method based on quantum annealing, namely SelectQA, is the most efficient for large problems in the multi-objective formulation, whereas QAOA-TCS offers the best trade-off between effectiveness and efficiency in the single-objective formulation when run on realistic noisy simulators. However, such analysis is constrained by the different computational environments used to run the algorithms.

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