The Report "Advancing a Global Framework for AI Safety and Governance for the Well-being of Humanity" is an important outcome of the AI Safety and Governance Program of World Internet Conference Specialized Committee on Artificial Intelligence in 2025. This report provides a systematic review of current global explorations and practices in AI safety and governance, identifies key issues that need to be addressed, and draws upon multilateral governance experiences from other domains. Centered on mechanism design, it explores how to build a global AI safety and governance system that ensures safety and security, promotes inclusiveness, clarifies responsibilities and accountabilities, strengthens effective coordination, and ensures authoritative and efficient governance. Guided by the principles of multilateralism and the vision of building a community with a shared future for humankind, the report proposes institutional measures and policy recommendations to establish a United Nations-centered global AI safety and governance framework. It aims to serve as a reference for governments, international organizations, enterprises, and research institutions. The report is to contribute insights and momentum to advancing people-centered and beneficial AI governance worldwide, ensuring that AI technologies truly serve the well-being of all humanity.

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