Psychological safety (PS) refers to the belief that team members can speak up, ask questions, and make mistakes without fear of negative consequences. Although PS has been studied in traditional software teams, less is known about how it may appear in pull-based open-source software development, where contributors are self-directed and often collaborate voluntarily. This paper introduces a theory-informed framework for understanding how PS may be reflected in pull request (PR) interactions. We investigate the framework through a mixed-methods approach combining repository-based analysis and a survey of OSS contributors. First, we constructed a PS index using nine observable PR interaction indicators extracted from 60,685 PRs across 26 GitHub repositories. Second, we surveyed 57 OSS contributors about their perceived PS and experiences of corresponding PR interactions. All nine surveyed interaction indicators were significantly and positively associated with perceived PS. However, the repository-based index was not significantly associated with survey-reported PS. Contributors' open-ended responses further highlighted the importance of feedback quality, opportunities to participate, and how PR outcomes are interpreted. Together, our framework and mixed-methods findings provide initial insights into how PS may be reflected in PR interactions, highlighting the importance of both PR interaction patterns and contributors' experiences.

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