metasnf is an R package that enables users to apply meta clustering, a method for efficiently searching a broad space of cluster solutions by clustering the solutions themselves, to clustering workflows based on similarity network fusion (SNF). SNF is a multi-modal data integration algorithm commonly used for biomedical subtype discovery. The package also contains functions to assist with cluster visualization, characterization, and validation. This package can help researchers identify SNF-derived cluster solutions that are guided by context-specific utility over context-agnostic measures of quality.
翻译:metasnf是一个R语言程序包,支持用户将元聚类方法应用于基于相似性网络融合(SNF)的聚类工作流。元聚类通过将聚类解本身作为聚类对象,实现对大规模解空间的高效搜索。SNF是一种常用于生物医学亚型发现的多模态数据整合算法。该程序包还包含辅助聚类可视化、特征描述与验证的功能模块,能够帮助研究者识别基于SNF的聚类解——这些解受特定情境效用的引导,而非通用的质量评估指标。