Metastases increase the risk of fracture when affecting the femur. Consequently, clinicians need to know if the patients femur can withstand the stress of daily activities. The current tools used in clinics are not sufficiently precise. A new method, the CT-scan-based finite element analysis, gives good predictive results. However, none of the existing models were tested for reproducibility. This is a critical issue to address in order to apply the technique on a large cohort around the world to help evaluate bone metastatic fracture risk in patients. Please see pdf file

翻译：转移瘤累及股骨会增加骨折风险，因此临床医生需要评估患者股骨能否承受日常活动应力。当前临床常用工具精度不足。一种基于CT扫描的有限元分析法可提供良好的预测效果，但现有模型均未经过复现性验证。要将该技术推广至全球大规模队列以评估患者骨转移性骨折风险，解决这一问题至关重要。详见PDF文件。