Synchrotron detectors generate data at rates that challenge storage and I/O systems. Compression can reduce data movement, but codec-only measurements do not capture the end-to-end behavior of HDF5 workflows. We present PhotonZip, a lifecycle-aware compression framework that tests candidate modes through a common HDF5 path and selects among eligible measured configurations according to either compression ratio or round-trip throughput. Its modular filters preserve standard HDF5 access when the required plugin is available. Across four beamline-derived datasets, PhotonZip reaches lossless compression ratios up to 1.629$\times$ and HDF5 write throughput up to 3.40GB/s write and 7.75GB/s read. The throughput-oriented configuration achieves 1.529$\times$ lossless data reduction while improving HDF5 write and read throughput by 21.2\% and 15.0\%, respectively. Lossy preview modes provide up to 16$\times$ data reduction and reduce preview latency by up to 8.35~s in the evaluated file-per-rank HDF5 configuration.

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