Survival models capture the relationship between an accumulating hazard and the occurrence of a singular event stimulated by that accumulation. When the model for the hazard is sufficiently flexible survival models can accommodate a wide range of behaviors. If the hazard model is less flexible, for example when it is constrained by an external physical process, then the resulting survival model can be much too rigid. In this paper I introduce a modified survival model that generalizes the relationship between accumulating hazard and event occurrence with particular emphasis on capturing thresholding behavior. Finally I demonstrate the utility of this approach on a physiological application.
翻译:生存模型描述了累积风险与该累积风险所引发的单一事件发生之间的关系。当风险模型具有足够灵活性时,生存模型能够适配广泛的行为模式。若风险模型灵活性不足(例如受外部物理过程约束时),生成的生存模型可能过于僵化。本文提出一种改进的生存模型,该模型推广了累积风险与事件发生之间的关系,特别强调对阈值行为的捕捉。最后,本文通过一项生理学应用实例验证了该方法的实用性。